20+ peer-reviewed journal articles, a book, and manuscripts in preparation spanning cancer metabolism, molecular diagnostics, cytogenetics, forensic genomics, and public health. Each recent entry has a short brief and a link to the full text.
A five-gene glutaminolysis signature fell with PTEN loss in all fourteen tumor types examined (significantly in twelve), and the decline was not MYC-mediated. It tracked chromosomal position: thirty-seven neighboring genes with no glutaminolysis annotation followed PTEN copy number as closely (mean rho 0.843 versus 0.842), which points to passenger co-deletion rather than metabolic regulation.
Of 914 blood cultures transcribed from a handwritten register, 20.7% yielded an organism. About 9.5% contained potentially significant organisms, and 11.2% met an organism-based contaminant rule, almost all Staphylococcus epidermidis alone. Recorded susceptibility among Gram-negative isolates was low for ceftazidime (5 of 24) and cefotaxime (1 of 12).
In a case-control study of 50 women with breast cancer and 150 without, awareness of aluminum in these products was low: 11.7% of controls and 10.0% of cases had noticed it in the ingredients. After age adjustment, product use for more than 10 years (OR 5.46), hormone replacement therapy and family history were associated with breast cancer. The authors note that the long-use association may reflect residual confounding and recall bias.
A questionnaire of 119 women and 50 randomly drawn culture reports from two Benghazi facilities showed that fungal infection was recorded most often at consultation (58.8%), whereas Streptococcus pyogenes was the leading culture isolate (22.0%), ahead of Candida (18.0%). The two samples were not linked, so this is a divergence between distributions, not a measure of diagnostic error. Unprescribed intravaginal antibiotic use was reported by 18.5%.
Among 214 breast cancer reports from three Libyan sources (2010–2022), ER was strongly positive in 54.1% and HER2 was 3+ in 21.8%. Among 191 reports classifiable by all four markers, luminal B-like was the most frequent subtype (46.1%), followed by luminal A-like (26.2%), triple-negative (14.7%) and HER2-overexpression (13.1%). Most reports (86.0% of those with known location) came from eastern Libya.
Among 27 patients with a sex-chromosome aneuploidy (19 Turner, 8 Klinefelter spectrum), median age at diagnosis was 14.5 years: 9.0 for Turner and 29.0 for Klinefelter syndrome, compared with about five weeks for Down syndrome in the same registry. The authors suggest earlier karyotyping of children with short stature or pubertal delay and of men with azoospermia.
Among 107 patients with known consanguinity and an interpretable karyotype, a chromosomal abnormality was found in 11 of 26 (42.3%) consanguineous and 37 of 81 (45.7%) non-consanguineous referrals (OR 0.87, 95% CI 0.36–2.13). Reproductive history and parental age did not differ, consistent with consanguinity raising risk chiefly for autosomal-recessive single-gene disorders rather than aneuploidy.
In 4,939 blood glucose measurements recorded in 2018 at a Benghazi hospital for surgery and accidents, mean glucose was higher in female than male patients (129.51 versus 123.42 mg/dL), with small effect sizes. A seasonal difference appeared, but record volume ranged from 67 to 754 per month, which suggests that sampling frequency rather than physiology explains the pattern.
Of 58 patients with Down syndrome (23.1% of 251 karyotyped referrals), 54 (93.1%) had free trisomy 21, three had a translocation and one had mosaicism. Median age at karyotyping was about five weeks, and median maternal age was 37.0 years, higher than among other referred patients (31.0 years; p = 0.008).
The study profiled 156,715 cancer-related records from Egypt, Morocco, Tunisia, Algeria and Libya indexed in OpenAlex. Output rose in all five countries, led by Egypt. Breast cancer was the most studied site (8,305 records), followed by liver (6,379); liver cancer made up 21% of Egypt's site-tagged records against a regional norm near 7%.
Libyan cancer research output did not fall after 2011 relative to four regional comparators (level change IRR 0.88, 95% CI 0.57–1.36), and its post-2011 slope exceeded the regional trend. International co-authorship declined (OR 0.73 per year), and the Arab regional share of international papers rose from 25% to 59% while the Western share fell from 55% to 44%.
Of 319 patients referred for karyotyping in eastern Libya (2021–2025), 251 had an interpretable karyotype and 106 (42.2%) had a clinically significant chromosomal abnormality. Down syndrome was the most frequent diagnosis (23.1% of the cohort). The detection rate fell from 80.4% in neonates to 15.1% in adults, which points to delayed recognition of some disorders.
In 197 men in Benghazi (30 with lung cancer, 122 traditional smokers, 45 electronic cigarette users), 93.3% of the patients reported smoking before diagnosis. Electronic cigarette users were younger, 71.1% of them also used other tobacco products (mainly waterpipe), and respiratory symptoms were least frequent in this group. This is a questionnaire-based comparison.
A retrospective review of 101 children aged 0–10 years diagnosed with meningitis at Benghazi Pediatric Hospital in 2024. Infants aged 3 to under 12 months were the largest group (47.5%), CSF culture was positive in 2.0% (attributed to prior antibiotic use), and overall mortality was 5.9%.
Among 302 women attending five outpatient clinics in Benghazi, 38.4% had adequate breast cancer knowledge. Although 85.8% were aware of breast self-examination, 21.2% practiced it regularly and 58.3% knew the correct technique. University education, prior attendance at awareness campaigns and family history independently predicted adequate knowledge.
Adult Porcellio laevis were exposed for 8 weeks to an insecticide (Cyperkill), a herbicide (Garlon) and a fungicide (Benlate), alone and in binary mixtures. Juvenile output and body weight dropped under all treatments, most with mixtures, and the highest mortality occurred with Cyperkill plus Garlon, which indicates synergistic toxicity.
Male Swiss albino mice received aqueous Datura stramonium leaf extract as single oral doses (12.5–200 mg/kg) or weekly sub-chronic doses for 28–40 days. There was no mortality. Lungs showed dose-dependent lesions (alveolar congestion, septal thickening, inflammatory infiltration), while cardiac histology was largely preserved. Recovery groups showed partial improvement.
Adding ammonium acetate or ammonium chloride to glutamine-starved Sp2/0-Ag14 mouse hybridoma cultures significantly increased viability, independent of the cells' ability to make glutamine. Ammonium salts did not prevent caspase-3 activation or cytochrome c leakage, but they reduced the number of cells with apoptotic nuclear fragmentation or condensation, so they appear to modulate late apoptotic events.
In Sp2/0-Ag14 hybridoma cells, which undergo apoptosis within minutes of glutamine deprivation, MCL-1 was the most highly expressed pro-survival BCL-2 family protein, and its level fell as glutamine starvation proceeded and viability dropped. The cells were more sensitive to obatoclax, which targets MCL-1, than to ABT-737, and obatoclax sensitized them to apoptosis after glutamine starvation.