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Daily Briefs and News

Short summaries of newly published papers and science news in molecular biology, molecular genetics, biotechnology and molecular therapeutics.

Features

Schematic of chromosome 10q23–q24 showing PTEN, the signature genes GLUD1 and GOT1, and 37 neighboring genes
Cancer Biology

Why a Glutaminolysis Signature Falls With PTEN Loss: Passenger Co-Deletion, Not Metabolic Regulation

Across 14 tumor types, a glutaminolysis signature fell with PTEN loss. Neighboring genes with no glutaminolysis role tracked PTEN just as closely, pointing to co-deletion on chromosome 10q.

2026 Read
Schematic: glutamine enters a cancer cell and ammonium is released
Cancer Biology

Ammonium Ions Improve Survival of Glutamine-Starved Hybridoma Cells Without Blocking Core Apoptosis Events

In glutamine-starved mouse hybridoma cells, ammonium salts raised viability and reduced nuclear fragmentation, yet did not block caspase-3 activation or cytochrome c release.

2026 Read
Schematic: obatoclax blocks MCL-1, BAK forms a pore and apoptosis follows
Molecular Biology

MCL-1 and Apoptosis: What Obatoclax Teaches Us About Cancer Cell Death

How the anti-apoptotic protein MCL-1 and the drug obatoclax shape the survival of glutamine-starved cells, in a mouse hybridoma model.

2026 Read
Sixteen dots, one per trial participant, colored by best response
Cancer Biology

Glutamine Plus Chemotherapy for Advanced Pancreatic Cancer: A Small Phase 1 Trial Finds the Combination Feasible

A phase 1 trial of oral glutamine with standard chemotherapy in 16 people with advanced pancreatic cancer reached its planned dose. It cannot show whether the combination works.

2026 Read
Skeletal formula of glutamine
Cancer Biology

Glutamine Addiction: Why Some Cancer Cells Depend on a Nonessential Amino Acid

Glutamine is an amino acid the body can make, yet many cancer cells in the laboratory fail to grow without it. What do we know about why?

2026 Read
Schematic: DNA is sequenced on a MiSeq FGx to produce an STR profile
Forensic Genomics

Reviving MiSeq FGx: Identifying Libya's Missing from the 2011 War

How our team restored a dormant forensic genomics system that went on to help identify remains of people missing since the 2011 conflict.

2024 Coming soon
Illustration: a book and graduation cap linked to four departments
Education

Reforming Biomedical Science Curricula: Lessons from Benghazi

Reflections on leading curriculum reform across four departments at the Faculty of Biomedical Sciences, University of Benghazi.

2024 Coming soon
Illustration: the isopod Porcellio laevis and agrochemical droplets
Toxicology

Agrochemical Mixtures and Porcellio laevis: A New Model for Environmental Toxicity

Why terrestrial isopods are valuable sentinel organisms for chronic and acute toxicity assessment of agricultural chemicals.

2023 Coming soon
Illustration: survey checklist, awareness ribbon and map pin
Public Health

Breast Cancer Awareness in Libya: What Our Benghazi Study Found

Key findings from our cross-sectional study on breast cancer awareness, early detection practices, and risk factor knowledge in Benghazi.

2026 Coming soon